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NSAIDs might lower the risk of bladder cancer

Non-steroidal anti-inflammatory drugs (NSAIDs), especially aspirin, may decrease the risk of bladder cancer according to a new study led by Dr. Margaret Karagas of Dartmouth Medical School.

The findings point to a decrease in risk for bladder cancer, especially advanced, high-grade tumors that contain alternations in the tumor suppressor protein TP53, with NSAID use. There was no correlation between the use of acetaminophen and risk of bladder cancer.

The study also showed an increased risk of cancer among users of phenacetin-containing analgesics, which were withdrawn in the 1980s.
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